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Letrozole

History

Letrozole is first developed by to combat the breast cancer. It is first come to usage in 1997 by the U.S. FDA approval and would hit the market by the commercial name as Femara.  It is much more popular by the name of Letrozole rather than its commercial name. While this substance is started to use for treating breast cancer, it has found a welcomed home among anabolic steroid users. Over the years, this substance is used to treat the breast cancer of post menopausal women.

 

What is Letrozole

Letrozole is a non steroidal oral aromatize substance for treating the hormonally responsive breast cancer surgery. It is commercially known as Femara. It works by reducing the total amount of estrogen produced primarily in the body.  It helps to prevent the breast cancer by controlling the production of estrogen. It is anti estrogenic in nature.

 

Used as medicine

This medication is used for treating certain types of breast cancers in women after menopause. Letrozole is used to prevent the breast cancer form returning and also controls the estrogen hormone. Because of this hormone is responsible to promote the breast cancer faster. This is also used to treat the women infertility.

 

Structural characteristic

The chemical name of Letrozole is Letrozole; 112809-51-5; Femara; Letrozol; 4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile; CGS 20267. The molecular formula of this substance is C17H11N5. Letrozole is a non steroidal oral aromatize substance for treating the hormonally responsive breast cancer surgery. It is commercially known as Femara.  It is a third generation aromatizes inhibitor to control the estrogen dependent breast cancer cells.


The side effects of Letrozole:

The usage of this supplement has enormous side effects.  Fatigue and weakness are the two most common side effects of using this substance. Apart from that the other side effects of using this supplement are:

·         Headaches

·         High blood pressure

·         Hot flashes

·         Joint pain

·         Depression

Hair loss, unusual sweating, nausea, sleeping disorders etc. are the other common side effects of using this substance. The excessive and prolonged usage of this supplement is also responsible for notably decrease in bone mineral content that increases the chances of Osteoporosis.

Another important side effect of such supplement is to reduce the good cholesterol level. It decreases the good cholesterol level and increases the bad cholesterol level.  So the users should accustom with cholesterol friendly diet is necessary which should be contained with immense amount of omega fatty acid. The users should also include plenty of cardio vascular training into their daily regime.

 

Administration of Letrozole:

In treatment of breast cancer the standard dosage of this supplement is 2.5 mg per day. This is the extremely potent dosage and will normally be administered until the cancer subsides.  For standard estrogenic protection 0.5-1 mg should be used every other day and it is more than enough. For the competitive body builders, a full 1 mg per day should be enough to get the stronger and harder look. This substance is applicable for men and women both and the dosage would remain the same. The supplement should be consumed with or without food once daily as directed by the doctor.


How Letrozole works in human body

·         This medication is used for treating some kinds of breast cancer in women after menopause.

·         This substance decreases the amount of estrogen which helps to grow the breast cancer faster.

·         Letrozole also prevent the breast cancer to return.

·          It protects the users from water retention and gynecomastia.

·         It helps to promote good and healthier cholesterol level.

·         Letrozole makes sure the users about the successful PCT.

·         It is quite preferred substance to treat low production of testosterone in human body.


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